Understanding the Mechanisms of Aging and Emerging Interventions
Aging is a complex biological process that affects every cell and system in the body, leading to a gradual decline in physiological function and an increased risk of chronic diseases. Recent scientific advancements have shed light on the underlying mechanisms of aging, spanning genetic, cellular, and systemic changes. These insights have paved the way for innovative interventions aimed at delaying or reversing the effects of aging. Mechanisms of Aging Aging is driven by interconnected processes that occur at multiple levels: Genetic and Molecular Changes: - DNA damage accumulates over time due to environmental stressors and reduced repair efficiency, leading to genomic instability. - Telomeres , the protective caps at the ends of chromosomes, shorten with each cell division. When they become critically short, cells enter a state of senescence or die. - Epigenetic changes, such as alterations in DNA methylation and histone modifications, disrupt gene ...