The Smell of Death: The Science Behind Cadaverine and Putrescine
The unmistakable, nauseating odor of death has fascinated and repelled humans for centuries. In the late 1800s, German physician Ludwig Brieger identified two key molecules responsible for this smell: cadaverine and putrescine . These compounds are formed during the decomposition of animal tissue, and their production is a fascinating mix of biology, chemistry, and microbial activity. What Are Cadaverine and Putrescine? Cadaverine and putrescine are foul-smelling organic compounds classified as diamines. They are produced when amino acids in proteins break down during decomposition: - Cadaverine is derived from the amino acid lysine through a process called decarboxylation, catalyzed by microbial enzymes like lysine decarboxylase. - Putrescine is formed from ornithine or arginine via similar enzymatic processes. Both compounds are released during the bloat and putrefaction stages of decomposition, when microorganisms feast on tissues and release gases that con...